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Regular Research Article|Articles in Press

Maintenance Psychotherapies for Older Adults: A Scoping Review

Published:February 12, 2023DOI:https://doi.org/10.1016/j.jagp.2023.02.001

      Highlights

      • What is the primary question addressed by this study? What is the state of the science on maintenance psychotherapies for depression, anxiety or both for black, Asian, and Latinx adults 60 years of age and older?
      • What is the main finding of this study? We found that maintenance psychotherapies in the treatment of depression, anxiety, or both have been under researched; and blacks, Asians, and Latinx older adults vastly underrepresented in studies. Nonetheless, the small body of knowledge signals that maintenance psychotherapies may have a role in maintaining recovery from depression.
      • What is the meaning of the finding? Despite depression and anxiety commonly and chronically affecting many older adults, maintenance psychotherapies remain under researched, greatly limiting our understanding of how to maintain the healthy functioning of older adults following recovery from these disorders.

      ABSTRACT

      Background/Objective

      Given the chronicity of depression and anxiety disorders in late life, maintenance treatments may have a role in preserving healthy functioning. This study aims to understand the state of the science on maintenance psychotherapies for Black, Asian, and Latinx older adults.

      Design

      Scoping review.

      Methods

      A priori protocol was prospectively published. Four databases were searched up to December 1, 2021. Eligible studies were conducted in the United States or Puerto Rico and focused on maintenance psychotherapies treating depression, anxiety, or both in adults 60+. Due to the underrepresentation of Black, Asian, and Latinx participants, studies were included irrespective of the participant's racial or ethnic background.

      Results

      A total of 3,623 unique studies were retrieved, and eight studies were included. Two studies represented randomized clinical trials, and six were studies of post hoc analyses. All studies were from the same research team, had similar maintenance treatments, and focused on depression. Studies included racially homogenous samples (94-98% White). The primary outcome was the recurrence of a major depressive episode. Across studies, maintenance psychotherapy shows promise in preventing the recurrence of depression in some older adults.

      Conclusion

      Expanding the scope of knowledge from achieving optimal functioning to sustaining those changes in older adults is a significant public health challenge given symptom recurrence. The small body of knowledge on maintenance psychotherapies shows a promising direction in maintaining healthy functioning following recovery from depression. However, opportunities remain to expand the evidence of maintenance psychotherapies with a more significant commitment to the inclusion of diverse populations.

      Key Words

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      References

        • Wilkinson P
        • Izmeth Z.
        Continuation and maintenance treatments for depression in older people.
        Cochrane Database Syst Rev. 2016; 9CD006727https://doi.org/10.1002/14651858.cd006727.pub3
        • Kok RM
        • Nolen WA
        • Heeren TJ.
        Efficacy of treatment in older depressed patients: a systematic review and meta-analysis of double-blind randomized controlled trials with antidepressants.
        J Affect Disord. 2012; 141: 103-115https://doi.org/10.1016/j.jad.2012.02.036
        • Schuurmans J
        • Comijs H
        • Emmelkamp PMG
        • et al.
        A randomized, controlled trial of the effectiveness of cognitive–behavioral therapy and sertraline versus a waitlist control group for anxiety disorders in older adults.
        Am J Geriatr Psychiatry. 2006; 14: 255-263https://doi.org/10.1097/01.JGP.0000196629.19634.00
        • Pinquart M
        • Duberstein PR.
        Treatment of anxiety disorders in older adults: a meta-analytic comparison of behavioral and pharmacological interventions.
        Am J Geriatr Psychiatry. 2007; 15: 639-651https://doi.org/10.1097/JGP.0b013e31806841c8
        • Deng Y
        • McQuoid DR
        • Potter GG
        • et al.
        Predictors of recurrence in remitted late-life depression.
        Depress Anxiety. 2018; 35: 658-667https://doi.org/10.1002/da.22772
        • Bryant C
        • Mohlman J
        • Gum A
        • et al.
        Anxiety disorders in older adults: looking to DSM5 and beyond….
        Am J Geriatr Psychiatry. 2013; 21: 872-876https://doi.org/10.1016/j.jagp.2013.01.011
        • Lenze EJ
        • Wetherell JL
        Anxiety disorders: new developments in old age.
        Am J Geriatr Psychiatry. 2011; 19: 301-304https://doi.org/10.1097/jgp.0b013e31820db34f
        • Lorimer B
        • Kellett S
        • Nye A
        • et al.
        Predictors of relapse and recurrence following cognitive behavioural therapy for anxiety-related disorders: a systematic review.
        Cogn Behav Ther. 2021; 50: 1-18https://doi.org/10.1080/16506073.2020.1812709
        • Porensky EK
        • Dew MA
        • Karp JF
        • et al.
        The burden of late-life generalized anxiety disorder: effects on disability, health-related quality of life, and healthcare utilization.
        Am J Geriatr Psychiatry. 2009; 17: 473-482https://doi.org/10.1097/jgp.0b013e31819b87b2
        • Gilman SE
        • Sucha E
        • Kingsbury M
        • et al.
        Depression and mortality in a longitudinal study: 1952-2011.
        Cmaj. 2017; 189: E1304-e1310https://doi.org/10.1503/cmaj.170125
        • Lenze EJ
        • Mulsant BH
        • Mohlman J
        • et al.
        Generalized anxiety disorder in late life: lifetime course and comorbidity with major depressive disorder.
        Am J Geriatr Psychiatry. 2005; 13: 77-80https://doi.org/10.1097/00019442-200501000-00011
        • Kok RM
        • Heeren TJ
        • Nolen WA
        Continuing treatment of depression in the elderly: a systematic review and meta-analysis of double-blinded randomized controlled trials with antidepressants.
        Am J Geriatr Psychiatry. 2011; 19: 249-255https://doi.org/10.1097/JGP.0b013e3181ec8085
        • Kok RM
        • Reynolds CF
        Management of depression in older adults: a review.
        JAMA. 2017; 317: 2114https://doi.org/10.1001/jama.2017.5706
      1. American Psychological Association. Clinical Practice Guideline for the Treatment of Depression Across Three Age Cohorts. 2019. Available at: https://www.apa.org/depression-guideline. Accessed October 3, 2022.

        • Raue PJ
        • Schulberg HC
        • Heo M
        • et al.
        Patients’ depression treatment preferences and initiation, adherence, and outcome: a randomized primary case study.
        Psychiatric Serv. 2009; 60: 337-343https://doi.org/10.1176/ps.2009.60.3.337
      2. JS Passel and D Cohn, U.S. Population Projections: 2005-2050, 2008, Pew Research Center. Available at: http://www.pewhispanic.org/2008/02/11/us-population-projections-2005-2050. Accessed October 3, 2022.

        • Byers AL
        • Yaffe K
        • Covinsky KE
        • et al.
        High occurrence of mood and anxiety disorders among older adults.
        Arch Gen Psychiatry. 2010; 67: 489https://doi.org/10.1001/archgenpsychiatry.2010.35
        • Gum AM
        • King Kallimanis B
        • Kohn R
        Prevalence of mood, anxiety, and substance-abuse disorders for older Americans in the national comorbidity survey-replication.
        Am J Geriatr Psychiatry. 2009; 17: 769-781https://doi.org/10.1097/JGP.0b013e3181ad4f5a
      3. Jiménez AL, Cruz-Gonzalez M, Calhoun TF, et al. Late life anxiety and depression symptoms, and suicidal behaviors in racial/ethnic minority older adults in community-based organizations and community clinics in the U.S. Cult Divers Ethnic Minority Psychol. Published online February 3, 2022. doi:10.1037/cdp0000524

        • Tricco AC
        • Lillie E
        • Zarin W
        • et al.
        PRISMA extension for Scoping Reviews (PRISMA-ScR): checklist and explanation.
        Ann Intern Med. 2018; 169: 467-473https://doi.org/10.7326/m18-0850
        • Peters MDJ
        • Godfrey C
        • McInerney P
        • et al.
        Chapter 11: Scoping Reviews (2020 version).
        in: Aromataris E Munn Z JBI Manual for Evidence Synthesis. JBI, 2020https://doi.org/10.46658/JBIMES-20-12
        • Sanchez Gonzalez M
        • Vasquez E
        • Alegria M
        Mental Health Continuation and Maintenance Interventions administered after mental health interventions for anxiety or depression in minority older adults: a scoping review.
        Open Sci Framew. 2021; (Published online November 25)https://doi.org/10.17605/OSF.IO/VAXUW
      4. Medical Library Association Latinx Cacus. Latinx/Hispanic US Population Search Hedges. 2021. Available at: https://scholarshare.temple.edu/handle/20.500.12613/6949. Accessed October 3, 2022.

        • Wilkinson P
        • Izmeth Z
        Continuation and maintenance treatments for depressive disorder in older adults.
        Cochrane Database Syst Rev. 2007; https://doi.org/10.1002/14651858.CD006727
      5. EndNote [Computer Software]. Version EndNote X9. Philadelphia, PA: Clarivate. 2013. Available at: https://endnote.com/. Accessed December 1, 2021.

      6. Covidence systematic review software [Computer Software]. Melbourne, Australia: Veritas Health Innovation. Available at: https://www.covidence.org/. Accessed December 2, 2021.

        • Reynolds III, CF
        • Frank E
        • Perel JM
        • et al.
        Nortriptyline and interpersonal psychotherapy as maintenance therapies for recurrent major depression: a randomized controlled trial in patients older than 59 years.
        JAMA. 1999; 281: 39https://doi.org/10.1001/jama.281.1.39
      7. Miller M, Frank E, Cornes C, et al. The value of maintenance interpersonal psychotherapy (IPT) in older adults with different IPT foci. Am J Geriatr Psychiatry. 11:97-102

        • Reynolds CF
        • Frank E
        • Dew MA
        • et al.
        Treatment of 70+-year-olds with recurrent major depression: excellent short-term but brittle long-term response.
        Am J Geriatr Psychiatry. 1999; 7: 64-69https://doi.org/10.1097/00019442-199924710-00009
        • Lenze EJ
        • Dew MA
        • Mazumdar S
        • et al.
        Combined pharmacotherapy and psychotherapy as maintenance treatment for late-life depression: effects on social adjustment.
        AJP. 2002; 159: 466-468https://doi.org/10.1176/appi.ajp.159.3.466
        • Dew MA
        • Reynolds CF
        • Mulsant B
        • et al.
        Initial recovery patterns may predict which maintenance therapies for depression will keep older adults well.
        J Affect Disord. 2001; 65: 155-166https://doi.org/10.1016/S0165-0327(00)00280-9
        • Reynolds CF
        • Dew MA
        • Pollock BG
        • et al.
        Maintenance treatment of major depression in old age.
        N Engl J Med. 2006; 354: 1130-1138https://doi.org/10.1056/NEJMoa052619
        • Dombrovski AY
        • Lenze EJ
        • Dew MA
        • et al.
        Maintenance treatment for old-age depression preserves health-related quality of life: a randomized, controlled trial of paroxetine and interpersonal psychotherapy.
        J Am Geriatr Soc. 2007; 55: 1325-1332https://doi.org/10.1111/j.1532-5415.2007.01292.x
        • Carreira K
        • Miller MD
        • Frank E
        • et al.
        A controlled evaluation of monthly maintenance interpersonal psychotherapy in late-life depression with varying levels of cognitive function.
        Int J Geriat Psychiatry. 2008; 23: 1110-1113https://doi.org/10.1002/gps.2031
        • First MB
        • Spitzer RL
        • Miriam G
        • et al.
        Structured Clinical Interview for DSM-IV Axis I Disorders: SCID-I: Clinical Version: Scoresheet.
        American Psychiatric Press, Washington DC1997 (Published online)
        • Lenze EJ
        • Wetherell JL
        A lifespan view of anxiety disorders.
        Dialog Clin Neurosci. 2011; 13: 381-399
        • Olfson M
        • King M
        • Schoenbaum M
        Benzodiazepine use in the United States.
        JAMA Psychiatry. 2015; 72: 136https://doi.org/10.1001/jamapsychiatry.2014.1763