- •What is the primary question addressed by this study?We explored the association between long-term trajectories of late-life loneliness and incident dementia.
- •What is the main finding of this study?Five distinct loneliness trajectories were found: long-term low, persistently decreasing, persistently increasing, long-term moderate, and long-term high. Compared with long-term low loneliness, persistently increasing, long-term moderate, and long-term high loneliness significantly increases the risk of dementia in older adults.
- •What is the meaning of the finding?To prevent dementia, we should pay attention to the elderly with long-term loneliness and persistently increasing loneliness, especially the elderly with long-term high loneliness.
Abbreviations:CES-D (Center for Epidemiologic Studies Depression Scale), CI (Confidence interval), ELSA (English Longitudinal Study of Ageing), GBTM (Group-based trajectory modeling), HR (Hazard ratio), IQCODE (Informant Questionnaire on Cognitive Decline in the Elderly), R-UCLA (Short 1980 version of the University of California, Los Angeles Loneliness Scale)
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