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Bad News and Good: Opioids are Associated with the Incidence of Dementia, but the Effect is Substantial Only for Those 75–80 Years of Age

      For decades the use of opioids both prescribed and otherwise has been the focus of intense scrutiny in the system of public health as well as criminal justice. Opioid related deaths have been climbing
      • Mattson CL
      • Tanz LJ
      • Quinn K
      • et al.
      Trends and geographic patterns in drug and synthetic opioid overdose deaths — United States, 2013-2019.
      with over 100,000 opioid related deaths in the United States in 2021. It is uncertain how many were intentional and how many accidental. Because prescribed opioids acutely dim one's awareness of pain it is reasonable to question their longer-term effects on cognitive risk. However existing studies offer conflicting results with only heavy chronic opioid use predictive.
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      References

        • Mattson CL
        • Tanz LJ
        • Quinn K
        • et al.
        Trends and geographic patterns in drug and synthetic opioid overdose deaths — United States, 2013-2019.
        MMWR Morb Mortal Wkly Rep. 2021; 70: 202-207https://doi.org/10.15585/mmwr.mm7006a4
      1. Moriya AS, and Fang Z. Any Use and “Frequent Use” of Opioids among Elderly Adults in 2018-2019, by Socioeconomic Characteristics. Statistical Brief #541. March 2022. Agency for Healthcare Research and Quality, Rockville, MD. https://meps.ahrq.gov/data_files/publications/st541/stat541.shtml. Accessed April 4, 2022.

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        http://dx.doi.org/10.14283/jpad.2021.15
        Date accessed: April 4, 2022
      2. Centers for Disease Control and Prevention (CDC). CDC Guideline for Prescribing Opioids for Chronic Pain. U.S. Department of Health and Human Services, CDC, Atlanta, Georgia.https://www.cdc.gov/drugoverdose/pdf/guidelines_at-a-glance-a.pdf. Accessed April 4, 2022.

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