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Letter to the Editor| Volume 30, ISSUE 9, P1051-1052, September 2022

Association of Vitamin K Insufficiency as Evaluated by Serum Undercarboxylated Osteocalcin With Depressive Symptoms in Community-Dwelling Older Adults

      Depressive symptoms are reduced by several nutritional components including L-methylfolate, S-adenosylmethionine, L-acetylcarnitine, N-acetylcysteine, and vitamin D.
      • Hoepner CT
      • McIntyre RS
      • Papakostas GI
      Impact of supplementation and nutritional interventions on pathogenic processes of mood disorders: a review of the evidence.
      Information on the association between vitamin K and depression is limited; two observational studies showed that reduced depressive symptoms are associated with a higher vitamin K intake evaluated by food-frequency questionnaire.
      • Nguyen TTT
      • Tsujiguchi H
      • Kambayashi Y
      Relationship between vitamin intake and depressive symptoms in elderly Japanese individuals: differences with gender and body mass index.
      ,
      • Bolzetta F
      • Veronese N
      • Stubbs B
      The relationship between dietary vitamin K and depressive symptoms in late adulthood: a cross-sectional analysis from a large cohort study.
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      References

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        • McIntyre RS
        • Papakostas GI
        Impact of supplementation and nutritional interventions on pathogenic processes of mood disorders: a review of the evidence.
        Nutrients. 2021; 13: 767
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        Relationship between vitamin intake and depressive symptoms in elderly Japanese individuals: differences with gender and body mass index.
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        The relationship between dietary vitamin K and depressive symptoms in late adulthood: a cross-sectional analysis from a large cohort study.
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