Advertisement
Brief Report| Volume 30, ISSUE 6, P727-732, June 2022

Download started.

Ok

Physical Health Burden Among Older Men and Women With Bipolar Disorder: Results From the Gage-Bd Collaboration

Published:December 10, 2021DOI:https://doi.org/10.1016/j.jagp.2021.12.006

      Highlights

      • What is the primary question addressed by this study? Are older adults with bipolar disorder more frequently affected by physical health problems than their peers, and does sex affect the frequency of physical health morbidity?
      • What is the main finding of this study? The prevalence of physical health problems is greater in women than men with bipolar disorder, and greater in men with than without bipolar disorder.
      • What is the meaning of the finding? Health services should ensure they address the physical health needs of older adults with bipolar disorder, more noticeably those affecting women.

      ABSTRACT

      Objectives

      To compare the prevalence of physical morbidities among men and women with older adult bipolar disorder (OABD), and men with and without OABD.

      Methods

      Cross-sectional analysis of the collaborative Global Aging & Geriatric Experiments in Bipolar Disorder (GAGE-BD) database and non-OABD data from the Health in Men Study. OABD defined as bipolar disorder among adults aged greater than or equal to 50 years. Outcomes of interest were diseases affecting the cardiovascular, respiratory, gastrointestinal, renal, musculoskeletal and endocrinological systems.

      Results

      We examined 1407 participants with OABD aged 50–95 years, of whom 787 were women. More women than men showed evidence of morbidities affecting the respiratory, gastrointestinal, musculoskeletal and endocrinological systems. More men with than without OABD showed evidence of cardiovascular, renal and endocrinological diseases.

      Conclusion

      GAGE-BD data showed that physical morbidities affect more women than men with OABD, and more men with than without OABD. The underlying reasons for these differences require clarification.

      Key Words

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to The American Journal of Geriatric Psychiatry
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Almeida OP
        • McCaul K
        • Hankey GJ
        • et al.
        Risk of dementia and death in community-dwelling older men with bipolar disorder.
        Br J Psychiatry. 2016; 209: 121-126
        • Sajatovic M
        • Strejilevich SA
        • Gildengers AG
        • et al.
        A report on older-age bipolar disorder from the international society for bipolar disorders task force.
        Bipolar Disord. 2015; 17: 689-704
        • Young AH
        • Grunze H
        Physical health of patients with bipolar disorder.
        Acta Psychiatr Scand Suppl. 2013; : 3-10
        • Almeida OP
        • Hankey GJ
        • Yeap BB
        • et al.
        Impact of a prudent lifestyle on the clinical outcomes of older men with bipolar disorder.
        Aging Ment Health. 2020; 24: 627-633
        • Almeida OP
        • Hankey GJ
        • Yeap BB
        • et al.
        Older men with bipolar disorder diagnosed in early and later life: physical health morbidity and general hospital service use.
        J Affect Disord. 2018; 241: 269-274
        • Beunders AJM
        • Kok AAL
        • Kosmas PC
        • et al.
        Physical comorbidity in older-age bipolar disorder (OABD) compared to the general population - a 3-year longitudinal prospective cohort study.
        J Affect Disord. 2021; 288: 83-91
        • Sajatovic M
        • Eyler LT
        • Rej S
        • et al.
        The global aging & geriatric experiments in bipolar disorder database (GAGE-BD) project: Understanding older-age bipolar disorder by combining multiple datasets.
        Bipolar Disord. 2019; 21: 642-649
        • Eyler LT
        • Aebi ME
        • Daly RE
        • et al.
        Understanding aging in bipolar disorder by integrating archival clinical research datasets.
        Am J Geriatr Psychiatry. 2019; 27: 1122-1134
        • Dols A
        • Rhebergen D
        • Beekman A
        • et al.
        Psychiatric and medical comorbidities: results from a bipolar elderly cohort study.
        Am J Geriatr Psychiatry. 2014; 22: 1066-1074
        • Crump C
        • Sundquist K
        • Winkleby MA
        • et al.
        Comorbidities and mortality in bipolar disorder: a Swedish national cohort study.
        JAMA Psychiatry. 2013; 70: 931-939