- •What is the primary question addressed by this study? What are the associations between geographic region and late-life depression (LLD) severity, item-level symptom burden, and treatment, and how do associations between race/ethnicity and LLD outcomes, previously observed in the overall sample, vary by geographic region?
- •What is the main finding of this study? We observed significant regional differences in LLD severity and item-level symptom burden, but not in treatment. Lower levels of LLD severity and item-level symptom burden were observed in the Midwest compared to the Northeast. Magnitudes of racial/ethnic disparities in LLD severity and item-level symptom burden, but not depression care, differed by region.
- •What is the meaning of the finding? LLD varied by geographic region. Furthermore, geographic region may play an important role in patterns of racial/ethnic disparities in LLD outcomes.
List of abbreviations:LLD (Late-life depression), US (United States), PA (Physical activity), PHQ (Patient health questionnaire), ZINB (Zero inflated negative binomial), FDR (False discovery rate), VITAL (VITamin D and OmegA-3 TriaL), VITAL-DEP (VITamin D and OmegA-3 TriaL-Depression Endpoint Prevention)
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Previous presentation: The Gerontological Society of America 2020 Annual Scientific Meeting, Virtual Conference, November 4-7, 2020.