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Severe Covid-19 Vaccine Side-Effects are Rare in Older Adults yet are Linked With Depressive Symptoms

Published:September 30, 2021DOI:https://doi.org/10.1016/j.jagp.2021.09.010
      COVID-19 vaccine development should have been the “light at the end of the tunnel.” However, antivaccinations attitudes and hesitation are common,
      • Berry SD
      • Johnson KS
      • Myles L
      • et al.
      Lessons learned from frontline skilled nursing facility staff regarding COVID-19 vaccine hesitancy.
      even among older adults. Such hesitancy has been positively associated with depression, potentially due to concerns about vaccine side-effects.
      • Palgi Y
      • Bergman YS
      • Ben-David B
      • et al.
      No psychological vaccination: vaccine hesitancy is associated with negative psychiatric outcomes among Israelis who received COVID-19 vaccination.
      We tested the association between depression and vaccine side-effects in older adults, and hypothesized that, like physical illness,
      • Agustini B
      • Lotfaliany M
      • Woods RL
      • et al.
      Patterns of association between depressive symptoms and chronic medical morbidities in older adults.
      depression should increase with each additional side-effect.
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