Subjective cognitive decline (SCD) is an early stage of cognitive impairment that
is mainly manifest as a subjective experience of cognitive worsening.
1
SCD is, for some individuals, an early clinical stage of Alzheimer's disease and
related dementias, preceding mild cognitive impairment. Thus, discovering therapeutic
interventions that can halt or reverse cognitive decline during early clinical stages
of a neurodegenerative disease, including SCD, are highly needed to reduce the burden
of Alzheimer's disease and related dementias on the individual and society.To read this article in full you will need to make a payment
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References
- A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease.Alzheimers Dement. 2014; 10: 844-852
- Non-pharmacologic interventions for older adults with subjective cognitive decline: systematic review, meta-analysis, and preliminary recommendations.Neuropsychol Rev. 2017; 27: 245-257
- Alleviated anxiety boosts memory training gain in older adults with subjective memory complaints: a randomized controlled trial.Am J Geriatr Psychiatry. 2022; 30: 184-194
- Design and rationale of the PACt-MD randomized clinical trial: prevention of Alzheimer's dementia with cognitive remediation plus transcranial direct current stimulation in mild cognitive impairment and depression.J Alzheimers Dis. 2020; 76: 733-751
Article info
Publication history
Published online: June 23, 2021
Accepted:
June 17,
2021
Received in revised form:
June 15,
2021
Received:
June 14,
2021
Footnotes
The data has not been previously presented orally or by poster at scientific meetings.
Identification
Copyright
© 2021 American Association for Geriatric Psychiatry. Published by Elsevier Inc. All rights reserved.