Subjective cognitive decline (SCD) is an early stage of cognitive impairment that is mainly manifest as a subjective experience of cognitive worsening.
1SCD is, for some individuals, an early clinical stage of Alzheimer's disease and related dementias, preceding mild cognitive impairment. Thus, discovering therapeutic interventions that can halt or reverse cognitive decline during early clinical stages of a neurodegenerative disease, including SCD, are highly needed to reduce the burden of Alzheimer's disease and related dementias on the individual and society.
- Jessen F
- Amariglio RE
- van Boxtel M
- et al.
A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease.
Alzheimers Dement. 2014; 10: 844-852
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Published online: June 23, 2021
Accepted: June 17, 2021
Received in revised form: June 15, 2021
Received: June 14, 2021
The data has not been previously presented orally or by poster at scientific meetings.
© 2021 American Association for Geriatric Psychiatry. Published by Elsevier Inc. All rights reserved.