Clinicians of a certain age, including this writer, who have had the privilege of developing longitudinal care relationships with scores of older depressed patients and their families, have experienced the joys, challenges and sorrows of working with this population. There is nothing like seeing a patient with depression severe enough to impair her usual activities and to cause her to pull back from her friends and extended family eventually turn the corner through a mix of meds, psychoeducation and therapy, and ultimately resume her daily life. However, not all patients experience a clear path to remission, with nonresponse, partial response, medication side effects, and ever-present psychosocial factors testing one's clinical skills. Sadly, we have also had the experience of working with an older patient and his family over many years, and then having a family member come forward with concerns about his memory slipping.
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- History of depression as a risk factor for dementia: an updated review.Aus N Zealand J Psychiatry. 2001; 35: 776-781
- History of depression as a risk factor for Alzheimer's disease.Epidemiol. 1995; 6: 366-369
- Longitudinal magnetic resonance imaging vascular changes, apolipoprotein E genotype, and development of dementia in the neurocognitive outcomes of depression in the elderly study.Am J Geriatr Psychiatry. 2007; 15: 839-849
- Change in stress and social support as predictors of cognitive decline in older adults with and without depression.Int J Geriatr Psychiatry. 2011; 26: 1267-1274
- Appetite and weight loss symptoms in late-life depression predict dementia outcomes.Am J Geriatr Psychiatry. 2016; 24: 870-878
- A twin study of late-onset depression and apolipoprotein E ε4 as risk factors for Alzheimer's disease.Biol Psychiatry. 1997; 41: 851-856
Kim D, Wang R, Kiss A. Depression and increased risk of Alzheimer's dementia: longitudinal analyses of modifiable risk and sex-related factors. Am J Geriatr Psychiatry
Published online: January 07, 2021
Accepted: January 3, 2021
Received: December 31, 2020
© 2021 Published by Elsevier Inc. on behalf of American Association for Geriatric Psychiatry.