Abstract| Volume 24, ISSUE 3, SUPPLEMENT , S171-S172, March 2016

Sertraline for the Treatment of Depression in Vascular Cognitive Impairment

      Introduction: Vascular cognitive impairment (VCI) refers to the effects of cerebrovascular disease (CVD) on cognition, from mild isolated deficits to dementia. VCI is the second most common cause of cognitive impairment in the elderly, behind Alzheimer disease. Depression is highly prevalent among patients with VCI, but little is known about its response to treatment. The purpose of this study was to determine whether or not sertraline, a commonly used antidepressant, would benefit patients with VCI and related depression.
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